More info
Overview
Long Name | Antibody Type | Antibody Isotype | Host | Species Reactivity | Validated Applications | Purification |
| protein phosphatase 3, regulatory subunit B, alpha | Monoclonal | IgG | Mouse | Bovine, Human, Rat | IHC-P, WB | Ascites |
Immunogen |
| Bovine brain calcineurin. |
Properties
Form | Liquid |
Size | 100 µg/vial |
Contents | Mouse ascites fluid, 1.2% sodium acetate, 2 mg BSA, with 0.01 mg NaN3 as preservative. *carrier free antibody available upon request. |
Concentration | |
Storage | At -20 °C for 12 months, as supplied, at 2-8 °C for one month. Avoid repeated freezing and thawing. |
Additional Information Regarding the Antigen
Gene | PPP3R1 |
Protein | Calcineurin subunit B type 1 |
Uniprot ID | Human(P63098), Mouse(Q63810), Rat(P63100) |
Function | Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity. |
Tissue Specificity | |
Sub-cellular localization | Cytoplasm, cytosol . Cell membrane . Cell membrane, sarcolemma. Note: Translocates from the cytosol to the sarcolemma in a CIB1- dependent manner during cardiomyocytes hypertrophy. |
Sequence Similarities | Belongs to the calcineurin regulatory subunit family. |
Aliases | CNA2|CNB|CNB1|CALNB1|Protein phosphatase 2B regulatory subunit 1|Protein phosphatase 3 regulatory subunit B alpha isoform 1 |
Application Details
| Application | Concentration* | Species | Validated Using** |
| Western blot | 0.25-0.5μg/ml | Human, bovine, rat | AssaySolutio's ECL kit |
| Immunohistochemistry(Paraffin-embedded Section) | 0.5-1μg/ml | Human, bovine, rat | AssaySolutio's IHC/ICC Detection kit |
AssaySolution recommends Mouse Chemiluminescent WB Detection Kit (AKIT003B) for Western blot, and Mouse Peroxidase IHC/ICC Detection Kit (AKIT004B) for IHC(P). *Blocking peptide can be purchased at $65. Contact us for more information
