ADAM19 Antibody View larger

ADAM19 Antibody

ASA-B0034

$330.00

More info

Overview

Long Name

Antibody Type

Antibody Isotype

Host

Species Reactivity

Validated Applications

Purification 

ADAM metallopeptidase domain 19PolyclonalIgGRabbitHuman, Mouse, RatIHC-P, WBImmunogen affinity purified.

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human ADAM19(286-298aa RRKLLAQKYHDNA), different from the related mouse sequence by one amino acid, and from the related rat sequence by two amino acids.

Properties

Form

Lyophilized

Size

100 µg/vial

Contents

Antibody is lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal and 0.05 mg NaN3. *carrier free antibody available upon request.

Concentration

Reconstitute with 0.2 mL sterile dH2O (500 µg/ml final concentration).

Storage

At -20 °C for 12 months, as supplied. Store reconstituted antibody at 2-8 °C for one month. For long-term storage, aliquot and store at -20 °C. Avoid repeated freezing and thawing.

Additional Information Regarding the Antigen

Gene

ADAM19

Protein

Disintegrin and metalloproteinase domain-containing protein 19

Uniprot ID

Q9H013

Function

Participates in the proteolytic processing of beta-type neuregulin isoforms which are involved in neurogenesis and synaptogenesis, suggesting a regulatory role in glial cell. Also cleaves alpha-2 macroglobulin. May be involved in osteoblast differentiation and/or osteoblast activity in bone (By similarity).

Tissue Specificity

Expressed in many normal organ tissues and several cancer cell lines.

Sub-cellular localization

Membrane; Single-pass type I membrane protein.

Sequence Similarities

Contains 1 disintegrin domain.

Aliases

A disintegrin and metalloproteinase domain 19(meltrin beta) antibody|A disintegrin and metalloproteinase domain 19 antibody|ADAM 19 antibody|ADAM metallopeptidase domain 19 antibody|Disintegrin and metalloproteinase domain containing protein 19 antibody|FKSG 34 antibody|FKSG34 antibody|MADDAM antibody|Meltrin beta antibody|Metalloprotease and disintegrin dentritic antigen marker antibody|MLTN B antibody|MLTNB antibody

Application Details

ApplicationConcentration*SpeciesValidated Using**
Western blot0.1-0.5μg/mlHuman, Rat MouseAssaySolutio's ECL kit
Immunohistochemistry(Paraffin-embedded Section)0.5-1μg/mlHuman, Rat MouseAssaySolutio's IHC/ICC Detection kit


AssaySolution recommends Rabbit Chemiluminescent WB Detection Kit (AKIT001B) for Western blot, and Rabbit Peroxidase IHC/ICC Detection Kit (AKIT002B) for IHC(P). *Blocking peptide can be purchased at $65. Contact us for more information

Anti-ADAM19 antibody, ASA-B0034, Western blotting
Lane 1: Rat Spleen Tissue Lysate
Lane 2: Rat Intestine Tissue Lysate
Lane 3: Rat Brain Tissue Lysate
Lane 4: HELA Cell Lysate
 
Anti-ADAM19 antibody, ASA-B0034, IHC(P)
Rat Spleen Tissue
 
Anti-ADAM19 antibody, ASA-B0034, IHC(P)
Human Lung Cancer Tissue
 

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