| Specificity |
reactive with Human Total Tie-2, reactivity with other related proteins not observed |
| Assay Range |
281-18000pg/ml |
| Sensitivity |
27 pg/ml |
| Storage |
2-8℃ |
| Background |
The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations；he TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis. TEK is closely related to the TIE receptor tyrosine kinase. |
| Assay duration |
4 hours |
| Assay format |
Sandwich |
| Alternative Name of Analyte |
Hyk；Tie2；tie-2；Cd202b；AA517024 |
