| Specificity |
reactive with Human Total MDM2, reactivity with other related proteins not observed |
| Assay Range |
281-18000pg/ml |
| Sensitivity |
27 pg/ml |
| Size |
96 Tests |
| Storage |
2-8℃ |
| Background |
Human Total MDM2 also known as E3 ubiquitin-protein ligase Mdm2 is a protein that in humans is encoded by the MDM2 gene.Mdm2 is an important negative regulator of the p53 tumor suppressor. Mdm2 protein functions both as an E3 ubiquitin ligase that recognizes the N-terminal trans-activation domain (TAD) of the p53 tumor suppressor and an inhibitor of p53 transcriptional activation. |
| Sample type |
serum, plasma, cell culture supernatant |
| Assay duration |
4 hours |
| Assay format |
Sandwich |
| Alternative Name of Analyte |
MDM2；ACTFS；HDMX；hdm2 |
