More info
Human adenoviruses (HAdVs) are classified into seven species (A-G), with more than 50 different types. Adenoviruses are commonly acquired by contact with secretions from an infected person or by contact with contaminated objects. In immunocompetent hosts, most adenovirus infections are asymptomatic; when infections are symptomatic, a broad spectrum of clinical manifestations is possible. The most common syndrome involves fever, sore throat, cough, rhinorrhea, or other respiratory symptoms. A separate syndrome involves conjunctivitis, pharyngitis, and fever (pharyngoconjunctival fever). Rare adenoviral syndromes in infants include severe bronchiolitis and pneumonia. Adenoviruses are frequently used as vectors for diverse applications including vaccination, treatment of cancer and hereditary disorders, cardiovascular applications, and stem cell research.