Macrophage Colony Stimulating Factor Human Recombinant, HEK ( M CSF Human, HEK )

Data sheet

Formulation

The M-CSF was lyophilized from a 0.2um filtered solution containing 0.67mg/ml in 1xPBS.

Solubility

It is recommended to reconstitute the lyophilized M-CSF in sterile 1xPBS containing 0.1% endotoxin-free recombinant HSA.

Purity

Greater than 95% as obsereved by SDS-PAGE.

Description

M-CSF Human Recombinant produced in HEK cells is a glycosylated homodimer, having a molecular weight range of 35-40kDa due to glycosylation.The M-CSF is purified by proprietary chromatographic techniques.

Protein Background

Granulocyte/Macrophage Colony-Stimulating Factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. MCSF i

Expression host

HEK.

Synonyms

Macrophage Colony Stimulating Factor, CSF-1, Lanimostim, MCSF, MGC31930, M-CSF.

Stability

Lyophilized M-CSF although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution M-CSF should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a

Physical Appearence

Sterile Filtered White lyophilized (freeze-dried) powder.

Biological Activity

The specific activity was determined by the dose-dependent stimulation of the proliferation of murine M-NFS-60 cells (Mouse Myeloid Leukemia indicator cell line) and is 1.13ng/ml.