Transforming Growth Factor-Beta 3 Human Recombinant ( TGF b 3 Human )

Data sheet

Formulation

The protein solution contains 20% Ethanol and 0.12% Acetic acid.

Purity

Greater than 96.0% as determined by SDS-PAGE.

Description

TGF-beta 3 Human Recombinant produced in E.Coli is a disulfide-linked homodimeric, non-glycosylated, polypeptide chain containing two 112 amino acid chains and having a total molecular mass of 25.5kDa. The TGF-b 3 is purified by standard chromatographic t

Protein Background

Transforming growth factor betas (TGF Betas) mediate many cell-cell interactions that occur during embryonic development. Three TGF Betas have been identified in mammals. TGF Beta 1, TGF Beta 2 and TGF Beta 3 are each synthesized as precursor proteins tha

Expression host

Escherichia Coli.

Synonyms

Transforming Growth Factor-beta3, TGFB3, ARVD, FLJ16571, TGF-beta3.

Reagent Appearance

Sterile Filtered clear solution.

Stability

TGF-beta 3 although stable at room temperature for 1 week, should be stored at 4°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).

Amino acid sequence

ALDTNYCFRN LEENCCVRPL YIDFRQDLGW KWVHEPKGYY ANFCSGPCPY LRSADTTHST VLGLYNTLNP EASASPCCVP QDLEPLTILY YVGRTPKVEQ LSNMVVKSCK CS.

Biological Activity

The activity is determined by the ability to induce chondrogenic differentiation.

References

1.Title: Altering the Architecture of Tissue Engineered Hypertrophic Cartilaginous Grafts Facilitates Vascularisation and Accelerates MineralisationPublication: DOI: 10.1371/journal.pone.0090716, March 04, 2014Link: http://www.plosone.org/article/info%3Ad