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Transforming Growth Factor-beta 3 Human Recombinant, CHO ( TGF b 3 Human, CHO )
DescriptionTGF-b 3 Human Recombinant produced in CHO is a disulfide-linked homodimeric, glycosylated, polypeptide chain containing 112 amino acids and having a molecular mass of 25kDa. The TGF-b 3 is purified by standard chromatographic
Data sheet
| Formulation | The protein solution contains 20% Ethanol and 0.1% Acetic acid. |
| Purity | Greater than 97.0% as determined by SDS-PAGE. |
| Description | TGF-b 3 Human Recombinant produced in CHO is a disulfide-linked homodimeric, glycosylated, polypeptide chain containing 112 amino acids and having a molecular mass of 25kDa. The TGF-b 3 is purified by standard chromatographic techniques. |
| Protein Background | Transforming growth factor betas (TGFBetas) mediate many cell-cell interactions that occur during embryonic development. Three TGFBetas have been identified in mammals. TGFBeta1, TGFBeta2 and TGFBeta3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecule. |
| Expression host | Chinese Hamster Ovarian Cells. |
| Synonyms | Transforming Growth Factor-beta3, TGFB3, ARVD, FLJ16571, TGF-beta3. |
| Reagent Appearance | Sterile Filtered clear solution. |
| Stability | TGF-beta 3 although stable at 4°C. for 3 weeks, should be stored at -20°C to -70°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). |
| Amino acid sequence | The sequence of the first five N-terminal amino acids was determined and was found to be Ala-Leu-Asp-Thr-Asn. |
| Biological Activity | The biological activity was determined using cell toxicity assay via HT-2 cells. The ED50 was found to be |