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HIV-2 Protease Recombinant ( HIV-2 Protease )
DescriptionHIV-2 protease is an active homodimer having a molecular mass of 10.7kDa.SourceEscherichia Coli.Physical AppearanceSterile filtered colorless clear solution.FormulationThe HIV-2 Protease solution (0.25mg/1ml) is formulated in 20mM Tris
Data sheet
| Formulation | The HIV-2 Protease solution (0.25mg/1ml) is formulated in 20mM Tris pH7.0, 20mM MES, 200mM NaCl, 1mM EDT, 0.5mM DTT, 0.05% PEG 8000and 10% glycerol. |
| Description | HIV-2 protease is an active homodimer having a molecular mass of 10.7kDa. |
| Protein Background | HIV-2 protease is very significant in the life cycle of the HIV virus. It is expressed in the infected cells as a part of Gag-Pol polyprotein from which it is auto-catalytycaly released after formation of an immature viral particle. The enzyme subsequently cleaves the other parts of viral polyproteins resulting in the maturation of the virus. In HIV-infected patients the enzyme is subjected to intensive mutagenesis and mutants resistant to applied medicines are produced as a result of the selection pressure. |
| Expression host | Escherichia Coli. |
| Reagent Appearance | Sterile filtered colorless clear solution. |
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.Please avoid freeze thaw cycles. |