More info
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Background: |
Cleavage of factor B by factor D causes the release of the Ba fragment and leaves the Bb fragment bound to C3b. This Bb subunit comes from the C-terminal of factor B and it contains the proteolytic active site of the serine protease C3b,Bb. C3b,Bb is called a C3 and a C5 convertase, because it converts both of these proteins to their active forms by cleaving off the small peptides C3a and C5a, respectively. |
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Storage: |
-70 C or below. Avoid freeze/thaw |
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Source: |
Normal human serum |
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Purity: |
>90% by SDS-PAGE |
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Molecular Weight: Size: |
60,000 Da (single chain) 250 µg/vial |
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Concentration: |
1.0 mg/mL |
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Buffer: |
Phosphate-buffered saline, pH 7.3 |
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Preservative:
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None, 0.22 µm filtered
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