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Background: | A major component of cobra venom is CVF which binds to the victim’s factor B and this is then activated by factor D forming CVF, Bb. CVF, Bb is a serine protease specific for the victim’s C3 and often C5 as well. The activity of this C3/C5 convertase is not affected by the complement regulatory proteins in blood and the complex is extremely stable. |
Storage: | -70℃ or below. Avoid freeze/thaw |
Source: | Normal human serum |
Activity: Purity: | >300 units >95% by SDS-PAGE |
Molecular Weight: Size: | 146,000 Da (multiple chains and isoforms) 1.0 mg/vial |
Concentration: | 1.0 mg/mL |
Buffer: | 10 mM sodium phosphate, 145 mM NaCl, pH 7.2 |
Preservative: Remark: | None, 0.22 µm filtered This product is only available in the U.S.A |