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Background: | Factor I is a naturally glycosylated serine protease which cleaves and inactivates C3b and C4b. Factor I is highly specific but inactive without a cofactor such as the soluble factor H and C4b binding protein (C4BP). |
Storage: | -70℃ or below. Avoid freeze/thaw |
Source: | Normal human serum |
Activity: Purity: | Cleaves C3b with factor H as a cofactor >95% by SDS-PAGE |
Molecular Weight: Size: | 88,000 Da (2 chains) 100 µg/vial |
Concentration: | 1.0 mg/mL |
Buffer: | 10 mM sodium phosphate, 145 mM NaCl, pH 7.3 |
Preservative: | None, 0.22 µm filtered |