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Background: | C3d is derived from human C3 after a series of proteolytic cleavages. Surface-bound C3d and its precursors C3dg and iC3b are recognized by complement receptor 2 (CR2, CD21) present on mature B cells and follicular dendritic cells which use these ligands to stimulate phagocytosis and antigen presentation to cells of the adaptive immune system. |
Storage: | -70℃ or below. Avoid freeze/thaw. |
Source: | Normal human serum |
Purity: | >95% by SDS-PAGE |
Molecular Weight: Size: | 33,800 Da (single chain) 100 µg/vial |
Concentration: | 1.0 mg/ml |
Buffer: | 10 mM Sodium phosphate, 145 mM NaCl, pH 7.3 |
Preservative: | None, 0.22 µm filtered |