CRISPR dCas9 guided gene activation and repression plasmid kit

GR-16611

$1,500.00

$1,500.00 per pair

Data sheet

Application The dCas9 fusion complex is directed to the transcriptional start site (TSS) region of a target gene by pairing between the associated single guide RNA (sgRNA) and the target locus to regulate gene expression.
Background The CRISPR-Cas9 has been repurposed for precise transcriptional regulation of target genes by fusing catalytically disabled Cas9 (dCas9) to transcriptional modulators .
Features pCMV-VPR-dCas9 for gene activation; pCMV-Krab-dCas9 for gene repression. 10 μg each.

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