Data sheet
| Formulation | MRAS protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 5mM DTT, 40% glycerol, 200mM NaCl and 2mM EDTA. |
| Purity | Greater than 90% as determined by SDS-PAGE. |
| Description | MRAS Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 225 amino acids (1-205 a.a.) and having a molecular mass of 25.7kDa. MRAS is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
| Protein Background | Ras-related protein M-Ras (MRAS) is a member of the RAS superfamily. These family members are membrane-anchored, intracellular signal transducers in charge of various normal cellular functions. They are oncogenically stimulated in a substantial fraction of tumors. MRAS serves as a significant signal transducer for novel upstream stimuli in controlling cell proliferation. |
| Expression host | E.coli. |
| Synonyms | Ras-related protein M-Ras, Ras-related protein R-Ras3, MRAS, RRAS3, M-RAs, R-RAS3. |
| Reagent Appearance | Sterile Filtered colorless solution. |
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Amino acid sequence | MGSSHHHHHH SSGLVPRGSH MATSAVPSDN LPTYKLVVVG DGGVGKSALT IQFFQKIFVP DYDPTIEDSY LKHTEIDNQW AILDVLDTAG QEEFSAMREQ YMRTGDGFLI VYSVTDKASF EHVDRFHQLI LRVKDRESFP MILVANKVDL MHLRKITREQ GKEMATKHNI PYIETSAKDP PLNVDKAFHD LVRVIRQQIP EKSQKKKKKT KWRGDRATGT HKLQC. |
More info
M-RAs, MRAS, Ras-related protein R-Ras3, RRAS3, R-RAS3, Ras-related protein M-Ras