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Epidermal Fatty Acid Binding Protein Human Recombinant ( FABP5 Human )

DescriptionRecombinant Human Epidermal Fatty Acid Binding Protein (FABP-5) is a monodimeric, non-glycosylated, polypeptide chain containing 135 amino acids and having a total molecular mass of 15200 Daltons.SourceEscherichia Coli.Physical

$193.00

Data sheet

Formulation Sterile filtered and lyophilized from 0.5 mg/ml in phosphate buffered saline.
Solubility Add 0.2 ml of dH20 and let the lyophilized pellet dissolve completely.
Purity Greater than 90% as determined by SDS PAGE.
Description Recombinant Human Epidermal Fatty Acid Binding Protein (FABP-5) is a monodimeric, non-glycosylated, polypeptide chain containing 135 amino acids and having a total molecular mass of 15200 Daltons.
Protein Background Human Fatty Epidermal Acid Binding Protein FABP also called FABP-5 is a 15 kD member of the intracellular fatty acid binding protein (FABP) family, which is known for the ability to bind fatty acids and related compounds ( bile acids or retinoids). In an internal cavity. The fatty acid binding proteins aP2 (fatty acid binding protein [FABP]-4) and mal1 (EFABP) are closely related and both are expressed in adipocytes. Absence of EFABP/mal1 resulted in increased systemic insulin sensitivity in two models of obesity and insulin resistance. Adipocytes isolated from mal1-deficient mice also exhibited enhanced insulin-stimulated glucose transport capacity. In contrast, mice expressing high levels of mal1 in adipose tissue display reduced systematic insulin activity.
Expression host Escherichia Coli.
Synonyms Fatty acid-binding protein epidermal, E-FABP, Fatty acid-binding protein 5, Psoriasis-associated fatty acid-binding protein homolog, PA-FABP, FABP5, EFABP, PAFABP.
Reagent Appearance Sterile Filtered lyophilized (freeze-dried) powder.
Stability Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid freeze-thaw cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C.
Purification Method Two-step procedure using size exclusion chromatography before and after refolding.

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