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Data sheet
| Size | 100ug/vial |
| Storage | At -20C for one year. After reconstitution, at 4C for one |
| Application | Cross ReactivityHuman, rat, rabbit. |
| Form | lyophilized |
| Ig type | mouse IgG3 |
| Immunogen/Antigen | Recombinant rabbit tryptophan hydroxylase. |
| Reconstitution | 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, |
| Clone | Try-63 |
| Cross Reactivity | Human, rat, rabbit. |
More info
Background
Tryptophan hydroxylase is the rate-limiting enzyme in the synthesis of serotonin (5-hydroxytryptamine, or 5HT). Tryptophan hydroxylaseatalyzes the biopterin-dependent monooxygenation of tryptophan to5-hydroxytryptophan (5HT), which is subsequently decarboxylated to form the neurotransmitter serotonin. Human tryptophan hydroxylase (TPH) is mapped to chromosome 11p15.3-p14 by in situ hybridization.
Tryptophan hydroxylase is the rate-limiting enzyme in the synthesis of serotonin (5-hydroxytryptamine, or 5HT). Tryptophan hydroxylaseatalyzes the biopterin-dependent monooxygenation of tryptophan to5-hydroxytryptophan (5HT), which is subsequently decarboxylated to form the neurotransmitter serotonin. Human tryptophan hydroxylase (TPH) is mapped to chromosome 11p15.3-p14 by in situ hybridization.