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Clone | NYRmCD28. |
Protein Background | CD28 co-stimulation is necessary for CD4 positive T-cell proliferation & survival, interleukin-2 production, and T-helper type-2 development. Human post-thymic regulatory T cells require CD28 co-stimulation to expand and maintain potent suppressive function in vivo. Apoptosis plays a key role in the age-related decline of CD28 expression and in immunosenescence. |
Type | Hamster Anti Mouse Monoclonal. |
Immunogen | Purified mouse purified mouse LN T cells. |
Ig Subclass | Hamster IgG. |
Purification Method | Protein-A. |
Storage Procedures | Lyophilized: store at 4°C. After reconstitution, if not intended for use within a month, aliquot and store at -20°C. |