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Tumor Necrosis Factor-alpha, Mouse-Anti Human ( TNF a Antibody )
TypeMouse Anti Human Monoclonal.CloneNYRhTNFa-E2.Immunogenr.Human TNF-a.Ig SubclassMouse IgG1.Purification Methodion exchange.Protein concentration1mg/ml in PBS (after reconstitution).Shipping ConditionsAntibody is shipped lyophilized at ambient
Data sheet
| Clone | NYRhTNFa-E2. |
| Applications | Direct ELISA, Western Blot, Immuneprecipitation, Intracellular staining. |
| Protein Background | Tumor necrosis factor is a cytokine involved in systemic inflammation and is a member of a group of cytokines that all stimulate the acute phase reaction. TNF is mainly secreted by macrophages. TNF causes apoptotic cell death, cellular proliferation, differentiation, inflammation, tumorigenesisand viral replication, TNF is also involved in lipid metabolism, and coagulation. TNF's primary role is in the regulation of immune cells.Dysregulation and, in particular, overproduction of TNF have been implicated in a variety of human diseases- autoimmune diseases, insulin resistance, and cancer. |
| Synonyms | TNF-alpha, Tumor necrosis factor ligand superfamily member 2, TNF-a, Cachectin, DIF, TNFA, TNFSF2. |
| Type | Mouse Anti Human Monoclonal. |
| Immunogen | r.Human TNF-a. |
| Ig Subclass | Mouse IgG1. |
| Purification Method | ion exchange. |
| Storage Procedures | In lyophilized form, for long periods, store at 4oC in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20oC. |