More info
Overview
Long Name | Antibody Type | Antibody Isotype | Host | Species Reactivity | Validated Applications | Purification |
| interleukin 1, beta | Polyclonal | IgG | Rabbit | Rat | ELISA | Immunogen affinity purified. |
Immunogen |
| A synthetic peptide corresponding to a sequence at the C-terminus of rat IL1 beta (202-229aa DPKQYPKKKMEKRFVFNKIEVKTKVEFE), different from the related human sequence by five amino acids, and from the related mouse sequence by one amino acid. |
Properties
Form | Lyophilized |
Size | 100 µg/vial |
Contents | Antibody is lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3. *carrier free antibody available upon request. |
Concentration | Reconstitute with 0.2 mL sterile dH2O (500 µg/ml final concentration). |
Storage | At -20 °C for 12 months, as supplied. Store reconstituted antibody at 2-8 °C for one month. For long-term storage, aliquot and store at -20 °C. Avoid repeated freezing and thawing. |
Additional Information Regarding the Antigen
Gene | IL1B |
Protein | Interleukin-1 beta |
Uniprot ID | Q63264 |
Function | Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. |
Tissue Specificity | |
Sub-cellular localization | Secreted. Note: The lack of a specific hydrophobic segment in the precursor sequence suggests that IL-1 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins. |
Sequence Similarities | |
Aliases | Catabolin antibody|H1 antibody|Hematopoietin 1 antibody|IFN beta inducing factor antibody|IL 1 antibody|IL 1 beta antibody|IL 1B antibody|IL-1 beta antibody|IL1 BETA antibody|IL1B antibody|IL1B_HUMAN antibody|IL1F2 antibody|Interleukin 1 beta antibody|Interleukin 1 beta precursor antibody|Interleukin-1 beta antibody|LAF antibody|OAF antibody|Osteoclast activating factor antibody| OTTHUMP00000162031 antibody| Preinterleukin 1 beta antibody|Preinterleukin beta antibody|Pro interleukin 1 beta antibody |
Application Details
| Application | Concentration* | Species | Validated Using** |
| ELISA | 0.1-0.5μg/ml | Rat | Sandwich ELISA format |
AssaySolution provides a series of assays reacted with primary antibodies. *Blocking peptide can be purchased at $65. Contact us for more information
