Specificity |
reactive with Human Total PTP1B, reactivity with other related proteins not observed |
Assay Range |
183-11700pg/ml |
Sensitivity |
17.55 pg/ml |
Size |
96 Tests |
Storage |
2-8℃ |
Background |
Tyrosine-protein phosphatase non-receptor type 1 also known as protein-tyrosine phosphatase 1B (PTP1B) is an enzyme that is the founding member of the protein tyrosine phosphatase (PTP) family. In humans it is encoded by the PTPN1 gene. PTP1B is a negative regulator of the insulin signaling pathway and is considered a promising potential therapeutic target, in particular for treatment of type 2 diabetes. |
Sample type |
serum, plasma, cell culture supernatant |
Assay duration |
4 hours |
Assay format |
Sandwich |
Alternative Name of Analyte |
PTPN1;PTP1B |