| Specificity |
reactive with Human Total PDGF R alpha, reactivity with other related proteins not observed |
| Assay Range |
281-18000pg/ml |
| Sensitivity |
27 pg/ml |
| Size |
96 Tests |
| Storage |
2-8℃ |
| Background |
Alpha-type platelet-derived growth factor receptor is a protein that in humans is encoded by the PDGFRA gene.This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies in knockout mice, where homozygosity is lethal, indicate that the alpha form of the platelet-derived growth factor receptor is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes |
| Sample type |
serum, plasma, cell culture supernatant |
| Assay duration |
4 hours |
| Assay format |
Sandwich |
| Alternative Name of Analyte |
CD140a；Pdgfr-2；AI115593 PDGFRA；CD140A；PDGFR-2；PDGFR2；RHEPDGFRA |
