| Specificity |
reactive with Human Total Erythropoietin R, reactivity with other related proteins not observed |
| Assay Range |
70-4500pg/ml |
| Sensitivity |
6.75 pg/ml |
| Size |
96 Tests |
| Storage |
2-8℃ |
| Background |
The erythropoietin receptor (EpoR) is a protein that in humans is encoded by the EPOR gene. EpoR is a 59 kDa peptide and is a member of the cytokine receptor family. EpoR pre-exists as dimers which upon binding of a 34 kDa ligand erythropoietin (Epo), changes its homodimerized state. These conformational changes result in the autophosphorylation of Jak2 kinases that are pre-associated with the receptor (i.e., EpoR does not possess intrinsic kinase activity and depends on Jak2 activity).At present, the most well-established function of EpoR is to rescue erythroid (red blood cell) progenitors from apoptosis. |
| Sample type |
serum, plasma, cell culture supernatant |
| Assay duration |
4 hours |
| Assay format |
Sandwich |
| Alternative Name of Analyte |
EPOR；EPO-R |
