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Mouse/ Rat Erythropoietin ( 15 ) ELISA Kit
NB-E10741
Mouse/ Rat Erythropoietin ( 15 ) ELISA Kit For research use only. Not for use in diagnostic procedures.For general protocol and instruction, please click the following links:Quantitative Elisa Kit InstructionSandwich ELISA kit general instruction
Data sheet
| Storage | 2 - 8 ℃ |
| Background | Erythropoietin, also known as hematopoietin or hemopoietin, is a glycoprotein cytokine secreted by the kidney in response to cellular hypoxia; it stimulates red blood cell production (erythropoiesis) in the bone marrow. Low levels of EPO (around 10 mU/mL) are constantly secreted sufficient to compensate for normal red blood cell turnover. Common causes of cellular hypoxia resulting in elevated levels of EPO (up to 10 000 mU/mL) include any anemia, and hypoxemia due to chronic lung disease. Erythropoietin is produced by interstitial fibroblasts in the kidney in close association with the peritubular capillary and proximal convoluted tubule. It is also produced in perisinusoidal cells in the liver. Liver production predominates in the fetal and perinatal period; renal production predominates in adulthood. Exogenous erythropoietin, recombinant Human erythropoietin (rhEPO) is produced by recombinant DNA technology in cell culture and are collectively called erythropoiesis-stimulating agents (ESA): two examples are epoetin alfa and epoetin beta. ESAs are used in the treatment of anemia in chronic kidney disease, anemia in myelodysplasia, and in anemia from cancer chemotherapy. Risks of therapy include death, myocardial infarction, stroke, venous thromboembolism, and tumor recurrence. Risk increases when EPO treatment raises hemoglobin levels over 11 g/dL to 12 g/dL for human, needs to be avoided. |
| Alternate Names | EP; EPO; epoetin; Erythropoietin; MGC138142; MVCD2 |
| Assay Type | Sandwich ELISA |
| Kit Type | Colorimetric |
| Assay Time | 4.5 hours |
| Sample Type | serum, plasma, cell culture supernatant |
| Assay Range | 6.25 - 400 mIU/ml |
| Sensitivity | 2.5 mIU/ml |
| Specificity | native and recombinant mouse, rat EPO |
More info
Human / Mouse/ Rat Erythropoietin ( 15 ) ELISA Kit
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Different lot may vary, please follow the instruction coming with the kit.