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Globular Adiponectin Mouse Recombinant ( gAcrp30 Mouse )
Patent RightsThe sale and/or commercial use of Recombinant Adiponectin is prohibited in the United States of America (U.S.A).DescriptionThe globular domain of Adiponectin Mouse Recombinant / Acrp30 Mouse contains 138 amino acid residues from a.a.
Data sheet
| Formulation | Acrp30 Mouse (1mg/ml) solution containing 20mM Tris-HCl pH7.5, 50mM NaCl, 5mM DTT and 10% Glycerol. |
| Purity | Greater than 95.0% as determined by SDS-PAGE. |
| Description | The globular domain of Adiponectin Mouse Recombinant / Acrp30 Mouse contains 138 amino acid residues from a.a. 111-247 having molecular mass of 16 kDa was over expressed in E.coli and purified by using conventional chromatography techniques. |
| Protein Background | Adiponectin (247amino acids) is adipocyte complement-related protein of 30 kDa and exclusively expressed in differentiated adipocytes. APM-1 (Acrp30 Mouse) is a member of the complement factor C1q family and consists of signal sequence, Non-homologous sequence, collagen domain and domain (gAcrp30). Adiponectin expression is reduced in a variety of obese and insulin-resistant states in human, monkeys and mice. Injection of Acrp30 Mouse (247aa) or gAcrp30 (globular domain) lowers serum glucose and free fatty acid level in mice. |
| Expression host | Escherichia Coli. |
| Synonyms | Acrp30, AdipoQ, GBP-28, APM-1, ACDC. |
| Reagent Appearance | Sterile filtered colorless solution. |
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| References | Title: Evidence that adiponectin receptor 1 activation exacerbates ischemic neuronal deathPublication: Experimental & translational stroke medicine 2.1 (2010): 15.Link: http://www.etsmjournal.com/content/2/1/15 |