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Adiponectin Mouse Recombinant, HEK ( Acrp30 Mouse, HEK )
Patent RightsThe sale and/or commercial use of Recombinant Adiponectin is prohibited in the United States of America (U.S.A).DescriptionThe Acrp30 Mouse Recombinant is fused with FLAG tag having a total Mw of 26kDa.SourceHEK293 (Human embryonic
Data sheet
| Formulation | Filtered (0.4um) and lyophilized from 0.5 mg/ml in PBS buffer. |
| Solubility | It is recommended to reconstitute the lyophilized Acrp30 Mouse in sterile 18M-cm H2O at 0.5mg/ml, which can then be further diluted to other aqueous solutions. |
| Purity | Purity of adiponectin mouse recombinant is >98% (HPLC and SDS PAGE analyzed). |
| Description | The Acrp30 Mouse Recombinant is fused with FLAG tag having a total Mw of 26kDa. |
| Protein Background | Adiponectin is an important negative regulator in hematopoiesis and immune systems. It may be involved in ending inflammatory responses through its inhibitory functions. Inhibits endothelial nf-kappa-b signaling through a camp-dependent pathway. Inhibits tnf-alpha- induced expression of endothelial adhesion molecules. Involved in the control of fat metabolism and insulin sensitivity. |
| Expression host | HEK293 (Human embryonic kidney cell line). |
| Synonyms | Acrp30, AdipoQ, GBP-28, APM-1, ACDC. |
| Stability | Store lyophilized APM-1 at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C. |
| Amino acid sequence | EDDVTTTEEL APALVPPPKG TCAGWMAGIP GHPGHNGTPG RDGRDGTPGE KGEKGDAGLL GPKGETGDVG MTGAEGPRGF PGTPGRKGEP GEAAYMYRSA FSVGLETRVT VPNVPIRFTK IFYNQQNHYD GSTGKFYCNI PGLYYFSYHI TVYMKDVKVS LFKKDKAVLF TYDQYQEKNV DQASGSVLLH LEVGDQVWLQ VYGDGDHNGL YADNVNDSTF TGFLLYHDTN DYKDDDDK. |
| Biological Activity | Full-length mouse adiponectin activates AMP-activated protein kinase in hepatocyte and activates AMPK in HepG2 human hepatocytes at a concentration of 1000ng/ml corresponding to a Specific Activity of 1000IU/mg. Mouse adiponectin mammalian cell derived inhibits glucose production as shown by in-vitro gluconeogenesis assay in primary rat hepatocytes. |