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H3N2 Influenza-A Virus Brisbane 10/07 ( H3N2 Brisbane )
DescriptionAllantoic fluid of 10 days old embryonated eggs, inoculated with influenza A virus, strain A/Brisbane/10/07. The Influenza Virus was purified by Ultracentrifugation with 10-40 % sucrose gradient.InactivationThimerosal and betaRecipient :
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Formulation | The H3N2 A/Brisbane/10/07 solution contains STE, 0.1% sodium azide (NaN3) and 0.005% thimerosal. |
Purity | Greater than 90.0% as determined byAnalysis by SDS-PAGE. |
Description | Allantoic fluid of 10 days old embryonated eggs, inoculated with influenza A virus, strain A/Brisbane/10/07. The Influenza Virus was purified by Ultracentrifugation with 10-40 % sucrose gradient. |
Protein Background | H3N2 is a subtype of the influenza A virus. Its name derives from the forms of the two kinds of proteinson the surface of its coat, hemagglutinin(H) and neuraminidase(N). H3N2 exchanges genes for internal proteins with other influenza subtypes. H3N2 has tended to dominate in prevalence over H1N1, H1N2, and influenza B. H3N2 strain descended from H2N2by antigenic shift, in which genes from multiple subtypes re-assorted to form a new virus. Both the H2N2and H3N2 strains contained genesfrom avian influenzaviruses. |
Reagent Appearance | Sterile Filtered whitish (milky) solution. |
Stability | A/Brisbane/10/07although stable 4°C for 4 weeks, should be stored below -18°C. Please prevent freeze-thaw cycles. |
References | Title: Broadly cross-reactive antibodies dominate the human B cell response against 2009 pandemic H1N1 influenza virus infectionpublication: The Rockefeller University Press, doi: 10.1084/jem.20101352 © 2011 Wrammert et al. Link:http://jem.rupress.org/content/early/2011/01/06/jem.20101352.full |