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Dengue Virus Subtype 2, Premembrane Recombinant ( Dengue Premembrane )
DescriptionRecombinant dengue 2 premembrane is a whole length peptide expressed from E. coil with 18kDa in size. PreM is considered as a signal peptide responsible for dengue envelope translocation in cells. Experiment showed it can elicit protective
Data sheet
| Formulation | 50mM phosphate buffer saline, pH-7.4. |
| Purity | Protein is >95% pure as determined by 12% PAGE (coomassie staining). |
| Description | Recombinant dengue 2 premembrane is a whole length peptide expressed from E. coil with 18kDa in size. PreM is considered as a signal peptide responsible for dengue envelope translocation in cells. Experiment showed it can elicit protective immune response, it is considered as a potentialtarget for vaccine development. Recombinant dengue 2 PreM is fused with a 6xHis tag. |
| Protein Background | Caused by one of four closely related virus serotypes of the genus Flavivirus, family Flaviviridae, each serotype is sufficiently different that there is no cross-protection and epidemics caused by multiple serotypes (hyperendemicity) can occur. In cell culture experiments and mice Morpholino antisense oligos have shown specific activity against Dengue virus. |
| Expression host | Escherichia Coli. |
| Reagent Appearance | Sterile filtered colorless solution. |
| Stability | Recombinant dengue 2 premembrane although stable at 4°C for 1 week, should be stored below -18°C. Please prevent freeze thaw cycles. |