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Hepatitis D Virus Recombinant ( HDV )
DescriptionThe E.Coli derived recombinant protein contains the HDV immunodominant regions, amino acids 1-108aa, 151-209aa.MethodPurified by proprietary chromatographic technique.PurityProtein is >90% pure as determined by 10% PAGE (Coomassie
Data sheet
| Storage | HDV although stable at 4°C for 1 week, should be stored below -18°C. Please prevent freeze thaw cycles. |
| Formulation | 50mM Tris pH 8 and 8M urea. |
| Purity | Protein is >95% pure as determined by 10% PAGE (Coomassie staining). |
| Description | The E.Coli derived recombinant protein contains the HDV immunodominant regions. |
| Protein Background | The HDV genome exists as a negative sense, single-stranded, closed circular RNA. Because of a nucleotide sequence that is 70% self-complementary, the HDV genome forms a partially double stranded RNA structure that is described as rod-like. With a genome of approximately 1700 nucleotides, It has been proposed that HDV may have originated from a class of plant viruses called viroids. Evidence in support of this hypothesis stems from the fact that both HDV and viroids exist as single-stranded, closed circular RNAs that have rod-like structures. Likewise, both HDV and viroids contain RNA sequences that can assume catalytically active structures called ribozymes. |