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Recombinant Human Papillomavirus 16 ( HPV 16 )
DescrptionThe Recombinant HPV-16 comprised from the E2, E6 & E7 epitopes is expressed in E. coli having an Mw of 33kDa. The protein is fused to a GST-Tag and purified by standard chromatography.SourceE.Coli.Purification MethodThe recombinantRecipient :
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Formulation | Recombinant HPV-16 solution in PBS, 100mM arginine and 3M Urea. |
Purity | Protein is >90% pure as determined by 10% SDS-PAGE (Coomassie staining). |
Protein Background | Human papillomavirus family consist of over 200 types. Over than 30 to 40 types of HPV are transferred via sexual contact and infect the anogenital region initiating genital warts. Persistent infection with "high-risk" HPV types results in skin warts and leads to precancerous lesions and invasive cancer. HPV infection is considered as a source for all incidents of cervical cancer. |
Expression host | E.Coli. |
Synonyms | Papillomavirus, HPV, Papilloma Virus. |
Stability | Recombinant HPV-16 although stable at 4°C for 1 week, should be stored below -18°C. Please prevent freeze thaw cycles. |
Amino acid sequence | MQVTFIYILVITCYENDVNVYHIFFQMSLWLPSEATVYLPPVPVSKVVSTDEYVARTNIYYHAGTSRLLAVGHPYFPIKKPNNNKILVPKVSGLQYRVFRIHLPDPNKFGFPDTSFYNPDTQRLVWACVGVEVGRGQPLGVGISGHPLLNKLDDTENASAYAANAGVDNRECISMDYKQTQLCLIGCKPPIGEHWGKGSPCTNVAVNPGDCPPLELINTVIQDGDMVHTGFGAMDFTTLQANKSEVPLDICTSICKYPDYIKMVSEPYGDSLFFYLRREQMFVRHLFNRAGTVGENVPDDLYIKGSGSTANLASSNYFPTPSGSMVTSDAQIFNKPYWLQRAQGHNNGICWGNQLFVTVVDTTRSTNMSLCAAISTSETTYKNTNFKEYLRHGEEYDLQFIFQLCKITLTADVMTYIHSMNSTILEDWNFGLQPPPGGTLEDTYRFVTQAIACQKHTPPAPKEDDPLKKYTFWEVNLKEKFSADLDQFPLGRKFLLQAGLKAKPKFTLGKRKATPTTSSTSTTAKRKKRKL. |
Purification Method | The recombinant HPV-16 fusion protein was purified by GSH affinity chromatography technique. |
Physical Appearence | Sterile filtered clear liquid formulation. |