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Interleukin-2 Human Recombinant, HEK ( IL 2 Human, HEK )
DescriptionInterleukin-2 Human Recombinant produced in HEK cells is a glycosylated monomer, having a total molecular weight of 15kDa.The IL2 is purified by proprietary chromatographic techniques.SourceHEK.Physical AppearenceSterile Filtered White
Data sheet
| Formulation | The IL2 was lyophilized from 1mg/ml in 1xPBS. |
| Solubility | It is recommended to reconstitute the lyophilized IL-2 in sterile PBS containing 0.1% endotoxin-free recombinant HSA. |
| Purity | Greater than 95% as obsereved by SDS-PAGE. |
| Description | Interleukin-2 Human Recombinant produced in HEK cells is a glycosylated monomer, having a total molecular weight of 15kDa.The IL2 is purified by proprietary chromatographic techniques. |
| Protein Background | IL2 is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. |
| Expression host | HEK. |
| Synonyms | T-cell growth factor (TCGF), Aldesleukin, Lymphokine, IL-2. |
| Stability | Lyophilized IL-2 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IL2 should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles. |
| Physical Appearence | Sterile Filtered White lyophilized (freeze-dried) powder. |
| Biological Activity | The specific activity was determined by the dose-dependent stimulation of the proliferation of mouse CTLL-2 cells (mouse cytotoxic T cell line) and is typically 0.2-2ng/ml. |