Human C3c protein

Background:

C3c is derived from iC3b (inactivated C3b) by proteolytic cleavage. iC3b is created by cleavage of C3b by factor I in the presence of factor H, CR1 or MCP.  C3c can be produced by an additional cleavage by factor I if the iC3b is bound to CR1. Factor H cannot serve as a cofactor for this cleavage. C3c can also be produced by the action of trypsin-like proteases on iC3b.

Storage:

-70℃ or below. Avoid freeze/thaw.

Source:

Normal human serum

Physical Appearance:

Frozen liquid

Purity:

>90% by SDS-PAGE

Molecular Weight:

Size:

139,000 Da (3 chains)

250 µg/vial

Concentration:

1.0 mg/ml

Buffer:

10 mM Sodium phosphate, 145 mM NaCl, pH 7.2

Preservative:

None, 0.22 µm filtered