Hepsin Antibody

Overview

Long Name	Antibody Type	Antibody Isotype	Host	Species Reactivity	Validated Applications	Purification
hepsin	Polyclonal	IgG	Rabbit	Human, Rat	WB	Immunogen affinity purified.
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human Hepsin(392-410aa KVSDFREWIFQAIKTHSEA), different from the related mouse sequence by two amino acids, and from the related rat sequence by one amino acid.

Properties

Form	Lyophilized
Size	100 µg/vial
Contents	Antibody is lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal and 0.05 mg NaN3. *carrier free antibody available upon request.
Concentration	Reconstitute with 0.2 mL sterile dH2O (500 µg/ml final concentration).
Storage	At -20 °C for 12 months, as supplied. Store reconstituted antibody at 2-8 °C for one month. For long-term storage, aliquot and store at -20 °C. Avoid repeated freezing and thawing.

Additional Information Regarding the Antigen

Gene	HPN
Protein	Serine protease hepsin
Uniprot ID	P05981
Function	Plays an essential role in cell growth and maintenance of cell morphology. May mediate the activating cleavage of HGF and MST1/HGFL. Plays a role in the proteolytic processing of ACE2.
Tissue Specificity	Present in most tissues, with the highest level in liver.
Sub-cellular localization	Membrane; Single-pass type II membrane protein.
Sequence Similarities	Belongs to the peptidase S1 family.
Aliases	EC 3.4.21. antibody|HEPS antibody|HEPS_HUMAN antibody|Hepsin antibody|HPN antibody|Serine protease hepsin antibody|Serine protease hepsin catalytic chain antibody|Serine protease hepsin non catalytic chain antibody|TMPRSS 1 antibody|TMPRSS1 antibody|Transmembrane protease serine 1 antibody

Application Details

Application	Concentration*	Species	Validated Using**
Western blot	0.1-0.5μg/ml	Human, Rat	AssaySolutio's ECL kit

AssaySolution recommends Rabbit Chemiluminescent WB Detection Kit (AKIT001B) for Western blot. *Blocking peptide can be purchased at $65. Contact us for more information