| Formulation |
The Mouse TGFB3 protein solution contains 20% Ethanol and 0.12% Acetic acid. |
| Purity |
Greater than 96.0% as determined by SDS-PAGE. |
| Description |
TGF-b3 Mouse Recombinant produced in E.Coli is a disulfide-linked homodimeric, non-glycosylated, polypeptide chain containing 112 amino acids and having a molecular mass of 25.5kDa. The TGF-b 3 is purified by standard chromatographic techniques. |
| Protein Background |
Transforming growth factor betas (TGF Betas) mediate many cell-cell interactions that occur during embryonic development. Three TGF Betas have been identified in mammals. TGF Beta 1, TGF Beta 2 and TGF Beta 3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecule. |
| Expression host |
Escherichia Coli. |
| Synonyms |
Transforming Growth Factor-beta3, TGFB3, ARVD, FLJ16571, TGF-beta3. |
| Reagent Appearance |
Sterile Filtered clear solution. |
| Stability |
Mouse TGF-beta 3 although stable at room temperature for 3 weeks, should be stored at 4°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). |
| Amino acid sequence |
ALDTNYCFRN LEENCCVRPL YIDFRQDLGW KWVHEPKGYY ANFCSGPCPY LRSADTTHST VLGLYNTLNP EASASPCCVP QDLEPLTILY YVGRTPKVEQ LSNMVVKSCK CS. |
| Biological Activity |
The activity is determined by the ability to induce chondrogenic differentiation. |
