IL34 Human, HEK

Data sheet

Formulation

The IL34 was lyophilized from a solution containing 20mM Sodium Citrate, pH 3.0 and 75mM NaCl.

Solubility

It is recommended to reconstitute the lyophilized Interleukin-34 in sterile 18M-cm H2O containing 0.1% endotoxin-free recombinant HSA.

Purity

Greater than 95.0% as determined by SDS-PAGE.

Description

Interleukin 34 Human Recombinant produced in HEK cells is a glycosylated homodimer, containing 460 amino acids and having a total molecular weight of 52.5kDa.The IL34 protein is fused to a His-tag at C-terminus & purified by proprietary chromatographic te

Protein Background

Interleukin 34 (IL34) is a cytokine that promotes the differentiation and viability of monocytes and macrophages through the colony-stimulating factor-1 receptor and is a part of a group of cytokines called interleukins. IL34 increases growth or survival

Expression host

HEK.

Synonyms

Interleukin 34, C16orf77, MGC34647, IL34.

Stability

Lyophilized IL34 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Interleukin 34 should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended t

Amino acid sequence

NEPLEMWPLT QNEECTVTGF LRDKLQYRSR LQYMKHYFPI NYKISVPYEG VFRIANVTRL QRAQVSEREL RYLWVLVSLS ATESVQDVLL EGHPSWKYLQ EVETLLLNVQ QGLTDVEVSP QGLTDVEVSP APGPNLKLVR PKALLDNCFR VMELLYCSCC KQSSVLNWQD CEVPSPQSCS PEPSLQYAAT QLYPPPPWSP SSPPHSTGSV RPVRAQGEGL LPHHHHHHHH.

Physical Appearence

Sterile Filtered White lyophilized (freeze-dried) powder.

Biological Activity

The specific activity was measured by its ability to induce secretion of MCP-1 from PBMCs.