CD95 Human, His

Data sheet

Formulation

8M urea, 20mM Tris-HCl, pH-8.0, 0.2M Imidazole, 0.01M b-ME.

Purity

Greater than 95% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.

Description

Recombinant FAS antigen/ CD95 purified from E. coli is a single non-glycosilated polypeptide chain containing amino acids 157-320 of Fas antigen (base pairs 713-1190 of cDNA sequence). The recombinant CD95 is fused to C-terminal 6-histidine amino acids.Th

Protein Background

FAS / CD95 is a 36kDa transmembrane type I receptor, which belongs to the NF/NGF receptor super-family. It is a potent inducer of apoptosis in cells of the immune system upon interaction with its natural ligand, CD95L. Although the CD95/CD95L system could

Expression host

Escherichia Coli.

Synonyms

CD95, CD-95, Tumor necrosis factor receptor superfamily member 6, FASLG receptor, Apoptosis-mediating surface antigen FAS, Apo-1 antigen, CD95 antigen, FAS, APT1, FAS1, TNFRSF6, APO-1, FASTM, ALPS1A.

Reagent Appearance

Sterile liquid formulation.

Stability

CD95 although stable at 10°C for 5 days, should be stored below -18°C.Please prevent freeze-thaw cycles.