| Formulation |
CD2 at 100ug/ml in 50mM Tris-HCl pH7.5 and 10Mm L-glutathione (reduced). |
| Applications |
ELISA. Inhibition Assays. Western Blotting. |
| Description |
CD2 Human Recombinant (aa 25-209) expressed in E.coli, shows a 46 kDa band on SDS-PAGE.The CD2 is purified by proprietary chromatographic techniques. |
| Protein Background |
CD2 which is also known as E-rosette receptor, T11 and lymphocytefunction antigen-2 (LFA-2) is expressed on T cells, thymocytes, and subset of natural killer cells. Human CD2 functions as the receptor for sheep erythrocytes, human CD58 (LFA-3), and CD15s (Sialyl Lewis X). p56lck, p59fyn, CD3eta and CD3epsilon are tyrosine-phosphorylated after CD2 stimulation. CD2 plays a role in T cell activation, T- or NK-cell-mediated cytolysis, apoptosis in activated peripheral T cells, and regulation of T cell anergy. |
| Expression host |
Escherichia Coli. |
| Synonyms |
T-cell surface antigen CD2, T-cell surface antigen T11/Leu-5, LFA-2, LFA-3 receptor, Erythrocyte receptor, Rosette receptor, CD2 antigen, CD2, T11, SRBC. |
| Reagent Appearance |
Sterile Filtered clear solution. |
| Stability |
Store vial at -20°C to -80°C. When stored at the recommended temperature, this protein is stable for 12 months.Please prevent freeze-thaw cycles. |
| Antibody Properties |
Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. |
| Available Conjugates |
Staining antibody. For staining, use 10ul/1,000,000 cells. |
| Immunological function |
This antibody is also available unconjugated to and conjugated to FITC. For staining with biotin or FITC-conjugated antibody use 5-10ul/1,000,000 cells. |
