Data sheet
| Reconstitution | 1mg/ml in PBS (after reconstitution). |
| Clone | hCD1a. |
| Protein Background | CD1a is a transmembrane glycoproteins, which is structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. CD1a mediates the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to the plasma membrane and to recycling vesicles of the early endocytic system. Alternatively spliced transcript variants have been observed, but their biological validity has not been determined. |
| Synonyms | T-cell surface antigen T6/Leu-6, hTa1 thymocyte antigen, R4, T6; CD1, FCB6, HTA1. |
| Type | Mouse Anti Human Monoclonal. |
| Immunogen | Purified human PBL T cells. |
| Ig Subclass | Mouse IgG1. |
| Purification Method | Ion exchange column. |
| Storage Procedures | Lyophilized: store at 4oC. After reconstitution, if not intended for use within a month, aliquot and store at -20oC. |
| Antibody Properties | Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. |
| Available Conjugates | FACS staining, immunohistochemistry, Western Blotting. For staining, use 10 ul/1,000,000 cells. |
| Immunological function | This antibody is also available unconjugated and conjugated to biotin. |
More info
FCB6, HTA1, hTa1 thymocyte antigen, R4, T6; CD1, T-cell surface antigen T6/Leu-6