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Hepatitis B surface Antigen A, Polyclonal Goat Antibody ( HBsAgA Antibody )
TypePolyclonal Goat Antibody.Product DescriptionAffinity-purified Goat antibodies against the Native Ad/AyHBsAg antigens.1mg/ml in PBS, was passed through a 0.2um Filter into a 50ml sterile conic Tube.StorageStore at -20C.StabilityOne year frozen.
Data sheet
| Storage | Store at -20C. |
| Formulation | (1ml) PBS. |
| Protein Background | Hepatitis B is one of a few known non-retroviralviruses which employ reverse transcriptionas a part of its replication process. (HIV, a completely unrelated virus, also uses reverse transcription, but it is a retrovirus.) HBV invades the cell by binding to surface receptor and become internalized. The viral core particles then migrate to the hepatocyte nucleus and the partially double-stranded, relaxed circular genomes (RC-DNA) are repaired to form a covalently closed circular DNA (cccDNA), which is the template for viral genomic and sub-genomic RNAs by cellular RNA polymerase II. Of these, the pregenomic RNA (pgRNA is selectively packaged into progeny capsids and is then reverse-transcribed into new RC-DNA. The core can either bud into the endoplasmic reticulum to be enveloped or exported from the cell or recycled back into the genome for conversion to cccDNA. |
| Reagent Appearance | Sterile Filtered solution. |
| Stability | One year frozen. One month in solution at 4C. |
| Type | Polyclonal Goat Antibody. |