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Hepatitis C Virus Core, Mouse antibody ( HCV Core Antibody )
TypeMouse antibody Monoclonal.ImmunogenRecombinant HCV peptide Mix.Ig SubclassMouse IgG1.SourceProtein-A.Clone#NYRHepC.Protein Concentration1mg/ml in PBS (After Reconstitution).Shipping ConditionsShipped lyophilized at ambient Temperature.Storage
Data sheet
| Clone | NYRHepC. |
| Applications | Direct ELISA, Western Blot, Immuneprecipitation, immunohistochemistry. |
| Protein Background | HCV is a small 50nm, enveloped, single-stranded, positive sense RNA virus in the family Flaviviridae. HCV has a high rate of replication with approximately one trillion particles produced each day in an infected individual. Due to lack of proofreading by the HCV RNA polymerase, the HCV has an exceptionally high mutation rate, a factor that may help it elude the host's immune response. Hepatitis C virus is classified into six genotypes (1-6) with several subtypes within each genotype. The preponderance and distribution of HCV genotypes varies globally. Genotype is clinically important in determining potential response to interferon-based therapy and the required duration of such therapy. Genotypes 1 and 4 are less responsive to interferon-based treatment than are the other genotypes (2, 3, 5 and 6). |
| Expression host | Protein-A. |
| Type | Mouse antibody Monoclonal. |
| Immunogen | Recombinant HCV peptide Mix. |
| Ig Subclass | Mouse IgG1. |
| Storage Conditions | In lyophilized form, for long periods, store at 4°C in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20°C. |
| Instructions for Use | The Recombinant HPV-16 antigen is a full length protein expressed in E. coli having an Mw of 56.7kDa. The protein is fused to a 26kDa GST-Tag, having a total Mw of 82.7kDA and purified by standard chromatography. |