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Polyclonal Anti-Annexin A2

FM-A10030

$320.00

Data sheet

Size 100ug/vial
Storage At -20C for one year. After reconstitution, at 4C for one month.
Form lyophilized
Ig type rabbit IgG
Immunogen/Antigen A synthetic peptide corresponding to a sequence in the middle region
Reconstitution 0.2ml of distilled water will yield a concentration of 500μg/ml.

More info

Background
Annexin A2 also known as annexin II is a protein that in humans is encoded by the ANXA2 gene. The ANXA2 gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. This protein is a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. Richard et al. (1994) presented an integration of the physical, expression, and genetic maps of human chromosome 15. They placed the ANXA2 gene in their region IV, i.e., 15q21-q22, thus confirming the previous localization.

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