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Reconstitution | 1mg/ml in PBS (after reconstitution). |
Clone | hCD14. |
Protein Background | CD14 (also known lipopolysaccharide (LPS) receptor) is expressed strongly on monocytes and macrophage and weakly on the surface of neutrophils. CD14 is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a high affinity receptor for complexes of LPS and LPS binding protein (LBP). Soluble CD14, also binding to LPS, acts at physiological concentration as an LPS agonist and has, at higher concentrations, an LPS antagonizing effect in cell activation. CD14 has been shown to bind apoptotic cells. |
Synonyms | Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein. |
Type | Mouse Anti Human Monoclonal. |
Immunogen | Purified human B Cells Ig SubclassMouse IgG1. |
Purification Method | Ion exchange column. |
Storage Procedures | Lyophilized: store at 4°C. After reconstitution, if not intended for use within a month, aliquot and store at -20°C. |
Antibody Properties | Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. |
Available Conjugates | Staining antibody. For staining, use 10ul/1,000,000 cells. |
Immunological function | This antibody is also available unconjugated and Biotin conjugated. For staining with biotin or FITC-conjugated antibody use 5-10ul/106 cells. |