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CD86, Rat Anti-Mouse ( CD86 Antibody )
TypeRat Anti Mouse Monoclonal.ClonemB7-2.ImmunogenPurified mouse LPS-activated B cells.Ig SubclassRat IgG2a.Purification MethodProtein-A.Protein concentration1mg/ml in PBS (after reconstitution).Storage ProceduresLyophilized: store at 4°C. After
Data sheet
| Reconstitution | 1mg/ml in PBS (after reconstitution). |
| Clone | mB7-2. |
| Protein Background | CD86 type I membrane protein is a member of the immunoglobulin superfamily which is expressed by antigen-presenting cells, and acts as the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. CD86 binding with CD28 protein is a co-stimulatory signal for initiation of the T-cell. CD86 binding with CTLA-4 negatively regulates T-cell activation and diminishes the immune response. |
| Synonyms | B70, B7-2, LAB72, CD28LG2, FUN-1, BU63. |
| Type | Rat Anti Mouse Monoclonal. |
| Immunogen | Purified mouse LPS-activated B cells. |
| Ig Subclass | Rat IgG2a. |
| Purification Method | Protein-A. |
| Storage Procedures | Lyophilized: store at 4°C. After reconstitution, if not intended for use within a month, aliquot and store at -20°C. |
| Antibody Properties | Reconstitute with H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. |
| Titer | Antibody is shipped lyophilized at ambient temperature. |
| Protein content | By direct ELISA, 1:10,000 dilution will yield 0.5 O.D using alkaline phosphatase conjugated rabbit anti-mouse Ig (Jackson Laboratories). |
| Application And Suggested Dilutions | Minimal cross-reactivity with human Luteinizing Hormone ?-Core fragment. |