View larger
Eotaxin-2, Mouse Anti Human ( Eotaxin 2 Antibody )
TypeMouse Anti Human Monoclonal.CloneNYRhEOT2.Immunogenr.Human Eotaxin-2.Ig SubclassMouse IgG.Purification MethodIon exchange.Protein concentration1mg/ml in PBS (after reconstitution).Shipping ConditionsAntibody is shipped lyophilized at ambient
Data sheet
| Clone | NYRhEOT2. |
| Applications | Direct ELISA, Western Blot, Immuneprecipitation. |
| Protein Background | Eotaxin-2, also called MPIF2 & Ck?6, is a novel CC chemokine produced by activated monocytes and T lymphocytes. Eotaxin-2 selectively chemoattracts cells expressing CCR3 including eosinophils, basophils, Th2 T cells, mast cells, and certain subsets of dendritic cells. Furthermore, Eotaxin-2 inhibits the proliferation of multipotential hematopoietic progenitor cells. The mature protein, which includes C-terminal truncation, contains 78 amino acids (92 amino acids for the mouse homolog, without C-terminal truncation).CCL24 functions as a chemotactic chemokine for resting t-lymphocytes, and eosinophils. CCL24 has lower chemotactic activity for neutrophils but none for monocytes and activated lymphocytes. CCL24 is a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line and binds to CCR3. |
| Synonyms | C-C motif chemokine 24, Small-inducible cytokine A24, Myeloid progenitor inhibitory factor 2, CK-beta-6, Eosinophil chemotactic protein 2, Eotaxin-2, CCL24, Ckb-6, MPIF2, MPIF-2, SCYA24, Eotaxin2, CCL-24. |
| Type | Mouse Anti Human Monoclonal. |
| Immunogen | r.Human Eotaxin-2. |
| Ig Subclass | Mouse IgG. |
| Purification Method | Ion exchange. |
| Storage Procedures | In lyophilized form, for long periods, store at 4oC in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20oC. |