View larger
Hepatitis B Virus ( AD & AY Antigens ) AG-2 for Capture ELISA, Mouse antibody ( HBV AG-2 antibody )
TypeMouse antibody Monoclonal.CloneNYRHepB-2.Immunogenr.Hep B vaccine (BTG).Ig Subclassmouse IgG1.Purification MethodIon exchange column.Protein concentration1mg/ml in PBS (after reconstitution).Shipping ConditionsAntibody is shipped lyophilized at
Data sheet
| Clone | NYRHepB-2. |
| Applications | Direct ELISA, Western Blot, Immuneprecipitation, immunohistochemistry. |
| Protein Background | Hepatitis B is one of a few known non-retroviralviruses which employ reverse transcriptionas a part of its replication process. (HIV, a completely unrelated virus, also uses reverse transcription, but it is a retrovirus.) HBV invades the cell by binding to surface receptor and become internalized. The viral core particles then migrate to the hepatocyte nucleus and the partially double-stranded, relaxed circular genomes (RC-DNA) are repaired to form a covalently closed circular DNA (cccDNA), which is the template for viral genomic and sub-genomic RNAs by cellular RNA polymerase II. Of these, the pregenomic RNA (pgRNA is selectively packaged into progeny capsids and is then reverse-transcribed into new RC-DNA. The core can either bud into the endoplasmic reticulum to be enveloped or exported from the cell or recycled back into the genome for conversion to cccDNA. |
| Type | Mouse antibody Monoclonal. |
| Immunogen | r.Hep B vaccine (BTG). |
| Ig Subclass | mouse IgG1. |
| Purification Method | Ion exchange column. |
| Storage Procedures | In lyophilized form, for long periods, store at 4°C in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20°C. |