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Macrophage Inflammatory-1 alpha, Mouse Anti-Human ( MIP 1a Antibody )
TypeMouse Anti Human Monoclonal.CloneYNR-HMIP1a.Immunogenr.Human MIP1-a.Ig SubclassMouse IgG1.Purification MethodIon exchange.Protein concentration1mg/ml in PBS (after reconstitution).Shipping ConditionsAntibody is shipped lyophilized at ambient
Data sheet
| Clone | YNR-HMIP1a. |
| Applications | Direct ELISA, Western Blot, Immuneprecipitation. |
| Protein Background | Macrophage Inflammatory Proteins (MIP) belong to the family of chemotactic cytokines known as chemokines. In humans, there are two major forms, MIP-1a and MIP-1b that are now officially named CCL3 and CCL4 respectively. Both are major factors produced by macrophages after they are stimulated with bacterial endotoxins. They activate human granulocytes (neutrophils, eosinophilsand basophils) which can lead to acute neutrophilic inflammation. They also induce the synthesis and release of other pro-inflammatory cytokines such as interleukin 1(IL-1), IL-6 and TNF-a from fibroblasts and macrophages. The genes for CCL3 and CCL4 are both located on human chromosome 17. |
| Synonyms | Small inducible cytokine A3, CCL3, Macrophage inflammatory protein 1-alpha, MIP-1-alpha, Tonsillar lymphocyte LD78 alpha protein, G0/G1 switch regulatory protein 19-1, G0S19-1 protein, SIS-beta, PAT 464.1, chemokine (C-C motif) ligand 3, MIP1A, SCYA3, G0S19-1, LD78ALPHA. |
| Type | Mouse Anti Human Monoclonal. |
| Immunogen | r.Human MIP1-a. |
| Ig Subclass | Mouse IgG1. |
| Purification Method | Ion exchange. |
| Storage Procedures | In lyophilized form, for long periods, store at 4oC in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20oC. |