Specificity |
reactive with Mouse TRAIL, reactivity with other related proteins not observed |
Assay Range |
31.25-2000 pg/ml |
Sensitivity |
3 pg/ml |
Size |
96 Tests |
Storage |
2-8 ℃ |
Background |
In the field of cell biology, TNF-related apoptosis-inducing ligand (TRAIL), is a protein functioning as a ligand that induces the process of cell death called apoptosis.TRAIL is a cytokine that is produced and secreted by most normal tissue cells. It causes apoptosis primarily in tumor cells, by binding to certain death receptors. It has been used as a target of several anti-cancer therapeutics since the mid-1990s. These however have not shown significant survival benefit.TRAIL has also been designated CD253 (cluster of differentiation 253) and TNFSF10 (tumor necrosis factor (ligand) superfamily, member 10). |
Sample type |
serum, plasma, cell culture supernatant |
Assay duration |
4 hours |
Assay format |
Sandwich |
Alternative Name of Analyte |
TNFSF10;APO2L;Apo-2L;CD253;TL2;TRAIL |