VRL1 Antibody

Overview

Long Name	Antibody Type	Antibody Isotype	Host	Species Reactivity	Validated Applications	Purification
transient receptor potential cation channel, subfamily V, member 2	Polyclonal	IgG	Rabbit	Human	IHC-P, IHC-F, WB	Immunogen affinity purified.
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human VRL1(42-624aa QFQGEDRKFAPQIRVNLNYRK).

Properties

Form	Lyophilized
Size	100 µg/vial
Contents	Antibody is lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal and 0.05 mg NaN3. *carrier free antibody available upon request.
Concentration	Reconstitute with 0.2 mL sterile dH2O (500 µg/ml final concentration).
Storage	At -20 °C for 12 months, as supplied. Store reconstituted antibody at 2-8 °C for one month. For long-term storage, aliquot and store at -20 °C. Avoid repeated freezing and thawing.

Additional Information Regarding the Antigen

Gene	TRPV2
Protein	Transient receptor potential cation channel subfamily V member 2
Uniprot ID	Q9Y5S1
Function	Calcium-permeable, non-selective cation channel with an outward rectification. Seems to be regulated, at least in part, by IGF-I, PDGF and neuropeptide head activator. May transduce physical stimuli in mast cells. Activated by temperatures higher than 52 degrees Celsius; is not activated by vanilloids and acidic pH.
Tissue Specificity
Sub-cellular localization	Cell membrane ; Multi-pass membrane protein . Cytoplasm . Melanosome.
Sequence Similarities	Belongs to the transient receptor (TC 1.A.4) family. TrpV subfamily. TRPV2 sub-subfamily.
Aliases	MGC12549 antibody|Osm 9 like TRP channel 2 antibody|osm-9-like TRP channel 2 antibody|OTRPC2 antibody|Sac2b antibody|Sac2b(gene name) antibody|Stretch activated channel 2B antibody|Stretch-activated channel 2B antibody|Transient receptor potential cation channel subfamily V member 2 antibody|TrpV2 antibody|TRPV2_HUMAN antibody|Vanilloid receptor like protein 1 antibody|Vanilloid receptor-like protein 1 antibody|VRL 1 antibody|VRL antibody|VRL-1 antibody|VRL1 antibody

Application Details

Application	Concentration*	Species	Validated Using**
Western blot	0.1-0.5μg/ml	Human	AssaySolutio's ECL kit
Immunohistochemistry(Paraffin-embedded Section)	0.5-1μg/ml	Human	AssaySolutio's IHC/ICC Detection kit
Immunohistochemistry(Frozen Section)	0.5-1μg/ml	Human	AssaySolutio's IHC/ICC Detection kit

AssaySolution recommends Rabbit Chemiluminescent WB Detection Kit (AKIT001B) for Western blot, and Rabbit Peroxidase IHC/ICC Detection Kit (AKIT002B) for IHC(P) and IHC(F). *Blocking peptide can be purchased at $65. Contact us for more information