NMDAR2A Antibody

Overview

Long Name	Antibody Type	Antibody Isotype	Host	Species Reactivity	Validated Applications	Purification
glutamate receptor, ionotropic, N-methyl D-aspartate 2A	Polyclonal	IgG	Rabbit	Human, Mouse, Rat	IHC-P, WB	Immunogen affinity purified.
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human NMDAR2A(1360-1376aa, DHTSDNPFLHSHRDDQR), different from the related mouse sequence by three amino acids, and from the related rat sequences by four amino acids.

Properties

Form	Lyophilized
Size	100 µg/vial
Contents	Antibody is lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal and 0.05 mg NaN3. *carrier free antibody available upon request.
Concentration	Reconstitute with 0.2 mL sterile dH2O (500 µg/ml final concentration).
Storage	At -20 °C for 12 months, as supplied. Store reconstituted antibody at 2-8 °C for one month. For long-term storage, aliquot and store at -20 °C. Avoid repeated freezing and thawing.

Additional Information Regarding the Antigen

Gene	GRIN2A
Protein	Glutamate[NMDA] receptor subunit epsilon-1
Uniprot ID	Q12879
Function	NMDA receptor subtype of glutamate-gated ion channels possesses high calcium permeability and voltage-dependent sensitivity to magnesium. Activation requires binding of agonist to both types of subunits.
Tissue Specificity
Sub-cellular localization	Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein.
Sequence Similarities
Aliases	Glutamate[NMDA] receptor subunit epsilon 1 antibody|Glutamate[NMDA] receptor subunit epsilon-1 antibody|Glutamate receptor antibody|Glutamate receptor ionotropic N methyl D aspartate 2A antibody|GRIN 2A antibody|GRIN2A antibody|HNR2A antibody|N methyl D aspartate receptor channel, subunit epsilon 1 antibody|N Methyl D Aspartate Receptor Subtype 2A antibody|N methyl D aspartate receptor subunit 2A antibody|N-methyl D-aspartate receptor subtype 2A antibody|NMDA receptor subtype 2A antibody|NMDA Receptor Type 2A antibody|NMDAR 2A antibody|NMDAR2A antibody|NMDE1_HUMAN antibody|NR 2A antibody|NR2A antibody|OTTHUMP00000160135 antibody|OTTHUMP00000174531 antibody

Application Details

Application	Concentration*	Species	Validated Using**
Western blot	0.1-0.5μg/ml	Mouse, Rat Human	AssaySolutio's ECL kit
Immunohistochemistry(Paraffin-embedded Section)	0.5-1μg/ml	Rat Human, Mouse	AssaySolutio's IHC/ICC Detection kit

AssaySolution recommends Rabbit Chemiluminescent WB Detection Kit (AKIT001B) for Western blot, and Rabbit Peroxidase IHC/ICC Detection Kit (AKIT002B) for IHC(P). *Blocking peptide can be purchased at $65. Contact us for more information