Mucin-5AC Antibody

Overview

Long Name	Antibody Type	Antibody Isotype	Host	Species Reactivity	Validated Applications	Purification
mucin 5AC, oligomeric mucus/gel-forming	Polyclonal	IgG	Rabbit	Human	IHC-P, WB	Immunogen affinity purified.
Immunogen
E.coli-derived human Mucin-5AC recombinant protein (Position: D4848-H5030).

Properties

Form	Lyophilized
Size	100 µg/vial
Contents	Antibody is lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3. *carrier free antibody available upon request.
Concentration	Reconstitute with 0.2 mL sterile dH2O (500 µg/ml final concentration).
Storage	At -20 °C for 12 months, as supplied. Store reconstituted antibody at 2-8 °C for one month. For long-term storage, aliquot and store at -20 °C. Avoid repeated freezing and thawing.

Additional Information Regarding the Antigen

Gene	MUC5AC
Protein	Mucin-5AC
Uniprot ID	P98088
Function	Gel-forming glycoprotein of gastric and respiratoy tract epithelia that protects the mucosa from infection and chemical damage by binding to inhaled microrganisms and particles that are subsequently removed by the mucocilary system.
Tissue Specificity	Highly expressed in surface mucosal cells of respiratory tract and stomach epithelia. Overexpressed in a number of carcinomas. Also expressed in Barrett's esophagus epithelium and in the proximal duodenum.
Sub-cellular localization	Secreted.
Sequence Similarities	Contains 1 CTCK (C-terminal cystine knot-like) domain.
Aliases	Apomucin antibody|Gastric mucin antibody|LeB antibody|Lewis B blood group antigen antibody|Major Airway Glycoprotein antibody|MUC 5 antibody|MUC5 antibody|MUC5AC antibody|Mucin 5 subtype AC tracheobronchial antibody|Mucin 5 Subtypes A And C antibody|Mucin 5 subtypes A and C tracheobronchial/gastric antibody|Mucin 5AC antibody|Mucin 5AC oligomeric mucus/gel forming antibody|Mucin 5AC, oligomeric mucus/gel forming pseudogene antibody|TBM antibody|Tracheobronchial Mucin antibody

Application Details

Application	Concentration*	Species	Validated Using**
Western blot	0.1-0.5μg/ml	Human	AssaySolutio's ECL kit
Immunohistochemistry(Paraffin-embedded Section)	0.5-1μg/ml	Human	AssaySolutio's IHC/ICC Detection kit

AssaySolution recommends Rabbit Chemiluminescent WB Detection Kit (AKIT001B) for Western blot, and Rabbit Peroxidase IHC/ICC Detection Kit (AKIT002B) for IHC(P). *Blocking peptide can be purchased at $65. Contact us for more information